定量光激发荧光技术检测乳磨牙窝沟封闭效果的临床研究

Clinical study of using quantitative light-induced fluorescence to test pit and fissure sealant on primary molar teeth

目的应用定量光激发荧光技术(quantitative light-induced fluorescence,QLF),评价树脂EMBRACE WetBond及玻璃离子GC FujiⅦ在隔湿条件有限的情况下对幼儿窝沟封闭半年的效果。方法选取符合纳入标准的成都市3～5岁114名幼儿,随机分为两组。采用树脂EMBRACE WetBond及玻璃离子GC FujiⅦ2种材料对幼儿乳磨牙牙合面窝沟封闭。所有检查者拍摄封闭前、封闭后、3个月和6个月的QLF照片,对绿色荧光和红色荧光分别进行分析。结果 105名儿童完成了6个月的临床试验,共计封闭牙齿201颗。两组儿童封闭牙齿绿色荧光总荧光损失量(△Q)封闭后、3个月及6个月的差异均有统计学意义(P<0.05),两组儿童封闭牙齿红色荧光总量(R)除3个月与6个月的差异无显著性意义外(P=0.191),其余各次差异均有显著性意义(P<0.01)。结论 QLF能够有效地评价乳磨牙窝沟封闭效果,可作为预防龋齿的手段之一。

Objective To assess the effect of resin EMBRACE WetBond and glass ionomer GC Fuji VII as pit and fissure sealant on teeth of children under conditions of limited moisture isolation for 6 months, using QLF. Methods 114 children aged 3 to 5 years old who meet the inclusion criteria were recruited from Chengdu. The subjects were randomized into two groups. Using EMBRACE WetBond and GC Fuji VII as pit and fissure sealant between two groups. QLF images were taken of each tooth 3 months and 6 months after seal. Results 105 chldren completed the 6 months＇ clinical trial,and the number of sealed teeth was 201. The results showed statistically significant differences between sealed teeth of children in two treatment groups in total fluorescence loss of green fluorescence （AQ） af- ter seal,3 months and 6 months after seal（P 〈 0. 05）, and in total red fluorescence（R） （P 〈 0. 01 ） except in 3 months and 6 months after seal（ P =0. 191 ）. Conclusions QLF can effectively evaluate pit and fissure sealant on primary molar teeth, and it can be a monitoring means to prevent tooth decay.