儿童急性淋巴细胞白血病化疗后院内感染24例报道

Analysis of Nosocomial Infection in 24 Children with Acute Lymphoblastic Leukemia

目的探讨儿童急性淋巴细胞白血病(acute lymphoblastic leukemia,ALL)化疗后院内感染特点及药物选择.方法回顾性分析24例儿童ALL接受CCLG-2008ALL方案化疗院内感染的临床资料.结果院内感染率高达95.8%,呼吸系统为最常见感染部位,91.3%有发热临床感染症状.结论急性淋巴细胞白血病患儿接受CCLG-2008ALL方案化疗,骨髓缓解率高,但感染发生率高,感染程度重,及时而强有力的抗感染能有效提高患儿的生存率.

Objective To study characteristic of nosocomial infection in 24children with Acute lymphoblastic leukemia after chemotherapy and antibacterials selection. Method The clinical data of 24 children with ALL suffered nosocomial infections after CCLG-2008ALL regimen chemotherapy were analyzed. Results The nosocomial infection rate was 95.8%, the respiratory system was the most common site of infection, 91.3% of them had clinical symptoms of infection with fever. Conclusion The marrow remission rate is high giving CCLG-2008ALL regimen chemotherapy, but the nosocomial infections is also high, the infection is severe.The survival could be improved through timely and effective anti-infection treatment.