云南省HIV/AIDS患者中结核病筛查效果评价

The Evaluation of TB Patients Screening Effect in People Living with HIV/AIDS in Yunnan

目的分析云南省2010年及2011年HIV/AIDS患者中结核病筛查效果及全球基金双感防治项目对HIV/AIDS患者中发现结核病患者的影响.方法整理2010年及2011年云南省双感防治工作年报,从结核病管理信息系统导出双感患者病案,使用卡方检验分析各年间项目县与非项目县之间筛查率及检查率之间的差异.结果云南省2011年可疑症状筛查率及结核病检查率较2010年差异有统计学意义(P<0.01),项目地区HIV/AIDS患者中结核病可疑症状问卷筛查率及结核病检查率均优于非项目地区(P<0.01);非项目地区2011年工作成效优于2010年,仍低于项目地区;2010年及2011年,全省发现双感患者652例,项目地区550例,非项目地区102例;项目地区重症患者比例少于非项目地区,发现延迟天数亦较非项目地区短.结论及早从HIV/AIDS人群中发现结核病患者并给与规范治疗是提升双感患者生命质量的有效干预措施,全球基金双感防治工作模式在云南省取得较好效果,此模式可继续推广.

Objective To analyze the effect of TB patients screening in people living with HIV/AIDS in Yunnan province during 2010 and 201!, with or without Global Fund （GF）. Methods TB/HIV data collected through annual paper reports and China Irdormation System for Disease Control TB Information System between 2010 and 2011, were analyzed with Chi＇square test for finding the difference in seereening rates between the two years, and between GF counties and non-GF counties. Results By the end of 2011, TB screening rates and examining rates among HIV/AIDS were higher than 2010 （P〈0.001） , TB screening rates and TB examining rates in GF counties were significantly higher than non-GF counties （P〈0.00I）. Between 2010 and 2011, 652 TB/HIV co-infection patients were reported, 550 TB/HIV patients registered in GF counties and 102 registered in non-GF counties. In non-GF counties, bigger number of critically ill patients was found and total delay was much longer than GF counties. Conclusions Early detection of TB cases among people living with HIV and properly treatment management in time could improve the life quality of TB/HIV patients. The work pattern of TB/HIV co-infection control can achieve excellent effects in Yunnan province by the support of GF, and should be generalized in Yunnan province.