头颈部IgG4相关性疾病的临床及影像学诊断

Clinical and imaging diagnosis of IgG4-related disease in the head and neck

头颈部IgG4相关性疾病是新认识的一种多器官系统病变,临床上以血清IgG4升高、广泛的IgG4阳性淋巴浆细胞组织浸润、组织纤维化及皮质类固醇激素治疗有效为特征。在CT和MRI上也可呈现一些相对特征的表现,CT和MRI不仅能为头颈部IgG4相关性疾病的诊断及鉴别诊断提供有价值的信息,而且能为临床治疗方案的选择及其疗效、预后的评估提供帮助。

IgG4-related disease in the head and neck is a newly recognized multi-organ system disease characterized by elevated serum IgG4, infiltration of numerous IgG4-positive plasma cells, tissue fibrosis, and dramatic response to corticosteroid treatment. IgG4-related disease of the head and neck has some relative characteristics on CT and MRI, which can provide valuable information for the diagnosis and differential diagnosis, and are helpful for the clinical treatment, evaluation of therapeutic effects and prediction of prognosis.