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血清C-反应蛋白水平与妊娠期糖尿病的关联性 被引量：16

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摘要 目的:探讨血清高敏C反应蛋白(hs-CRP)水平与妊娠期糖尿病(GDM)的关系。方法:选取2008年12月至2011年10月在我院产检并分娩的203例孕妇为研究对象,根据75gOGTT结果分为葡萄糖耐量正常组(NGT组)和GDM组。测定两组血糖、血脂、血清胰岛素及血清hs-CRP水平,分析其与GDM的关系。结果:GDM组hs-CRP、空腹血糖、空腹胰岛素、胆固醇、甘油三酯和LDL-C均高于对照组,差异有统计学意义(P<0.05)。Logistic回归分析显示,CRP是影响GDM的危险因素;按hs-CRP四分位分组,CRP水平≥4.78mg/L与GDM的关联性具有统计学意义(P<0.05)。结论:GDM的发生、发展与炎症反应有关,hs-CRP水平增高是GDM发病和进展的重要标志之一。
作者 程飞 于莎莎
机构地区 首都医科大学附属北京世纪坛医院内分泌科 首都医科大学附属北京世纪坛医院产科
出处 《实用医学杂志》 CAS 北大核心 2013年第7期1149-1151,共3页 The Journal of Practical Medicine
关键词 糖尿病 妊娠 C反应蛋白 亚临床炎症 危险因素
分类号 R446.6 [医药卫生—诊断学] R714.25 [医药卫生—妇产科学]
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参考文献12

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共引文献55

同被引文献134

  • 1赵怿,杨慧霞,马海燕.妊娠合并糖代谢异常孕妇糖化血红蛋白水平与母儿合并症的关系[J].中华围产医学杂志,2005,8(5):306-308. 被引量：38
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引证文献16

二级引证文献143

实用医学杂志
2013年 第7期

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