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系统性红斑狼疮合并冠心病患者临床指标的观察分析 被引量:5

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摘要 目的:总结系统性红斑狼疮(SLE)合并冠心病的临床特点,探讨其危险因素及发病机制。方法:选择2009月10月-2012年10月在本院住院的SLE合并冠心病患者35例为观察组;对照组为单纯冠心病患者,排除所有结缔组织疾病,共35例。检测血生化指标并进行超声心动图检查,记录左室舒张末径、左心室射血分数,对所有指标进行回顾性分析。结果:SLE合并冠心病组患者血LP(a)、CRP的水平明显高于对照组(P<0.05),比较差异有统计学意义。SLE合并冠心病组患者的左室舒张末内径明显高于对照组(P<0.05),而左心室收缩功能低下比例明显高于对照组(P<0.05),差异有统计学意义。结论:传统致动脉粥样硬化的高危因素不足以解释SLE早期发生冠心病,SLE合并冠心病可能其独特的高危因素。炎症反应参与了SLE合并冠心病的发生发展过程。
出处 《中国医学创新》 CAS 2013年第9期142-143,共2页 Medical Innovation of China
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