布托啡诺复合丙泊酚静脉麻醉在无痛人流术中的应用

Butorphanol and propofol intravenous anesthesia for painless induced abortion

目的观察布托啡诺复合丙泊酚静脉麻醉在无痛人流术中的效果，评价其安全性，指导临床工作。方法利用SPSS统计软件包对240例病例按中心分层方法产生随机数，根据用药情况分为3组：P组，丙泊酚-生理盐水组；F组，丙泊酚-芬太尼组；B组，丙泊酚-布托啡诺组。监测三组的HR、MAP、SpO2，记录丙泊酚用量、苏醒时间，并对术中镇痛效果评级、术后宫缩痛进行VAS评分。结果和P组比较，F、B组患者HR、MAP下降低于P组（P〈0．05），其丙泊酚的用量减少、术中效果较好、术后宫缩痛VAS评分较低（P〈0．05）；与F组比较，B组SpO：高于F组（P〈0．05）。结论布托啡诺复合丙泊酚可安全有效应用于无痛人流术，值得推广和应用。

Objective To observe clinical efficacy and evaluate safety of butorphanol and propofol intravenous anesthesia for painless induced abortion so as to guide treatment. Methods 240 women undergoing painless induced abortion were randomly divided into three groups, group P adopting propofol only, group F adopting fentanyl and propofol, group B adopting butorphanol and propofol. Observed HR, MAP, Sp02, the dose of propofol, recovery time, intraoperative analgesic effect and postoperative uterine contraction pain VAS score of three groups. Results Compared with group P, HR, MAP, the dose of propofol, intraoperative analgesic effect and postoperative uterine contraction pain VAS score in group F, B were better （P 〈 0.05）. SpO2 of group B was higher than that of group F. Conclusion Butorphanol and propofol can be applied in painless induced abortion, worthy of promotion.