心脏骤停心肺复苏成功患者发生肾功能损伤的临床分析

Clinical analysis on renal function injury of patients after cardio arrest pulmonary resuscitation

目的研究心脏骤停复苏成功患者复苏后肾功能的发生情况。方法对我院2009—2012年间心脏骤停复苏成功的患者按心脏停搏时间分为A组（≤10min）和B组（〉10min），对两组患者复苏后肾功能情况进行观察，测定血肌酐（Ccr）、尿素氮（BUN）等水平变化情况。结果两组患者血BUN、Scr水平在复苏后即刻差异无显著陛（P〉0．05），复苏后3d内两组患者血BUN、Scr、尿RBC计数均呈现先上升后下降的变化趋势，在2d达高峰后逐渐下降，两组尿蛋白阳性率呈逐渐下降趋势。A组BUN、Scr升高程度和峰值、尿RBC计数、尿蛋白率等始终低显著于B组（P〈0．05）。结论心脏骤停后心肺复苏成功患者多存在肾功能损伤，且心脏停搏时间越长，损伤程度越严重。

Objective To study the renal function injury status after cardio pulmonary resuscitation （CPR）. Methods 46 cardiac arrest patients after CPR were divided according to the arrest time as group A（≤ 10min） and group B（ 〉 10min）. The 2 groups were observed in terms of serum creatinine （Scr）, blood urea nitrogen （BUN） and etc. Results The BUN, Scr, urine RBC of both groups showed a trend of ascending first and descending then, the peak appeared after 2 days. The urine protein rate of both groups decreased from the first day. Group A had a lower level of BUN, Scr, urine RBC and urine protein rate than those of group B （P〈0.05）. Conclusions The cardiac arrest patients after CPR commonly have renal function injury and the longer the heart stops the more severe the injury is.