喘可治注射液对慢性阻塞性肺疾病急性加重期患者动脉血气及血清C反应蛋白的影响

Effect of Chuankezhi injection on arterial blood gas and serum C-reactive protein of patients with acute exacerbation chronic obstructive pulmonary disease

目的观察喘可治注射液对慢性阻塞性肺疾病急性加重期患者动脉血气分析和血清C反应蛋白（CRP）的影响。方法选取老年慢性阻塞性肺疾病急性加重期患者45例，分为治疗组（23例）及对照组（22例），治疗组肌肉注射喘可治注射液，每次4ml，每日2次，1周为1疗程。用药前、用药第4天及用药后分别进行血气指标及血清CRP测定。结果治疗组PaO2上升水平高于对照组（P〈0．05），CRP水平较对照组明显下降（P〈0．05）。结论喘可治注射液能够明显改善慢性阻塞性肺疾病急性加重期患者血气指标Paoz及血清CRP水平。

Objective To observe the effect of Chuankezhi injection on arterial blood gas analysis and serum C-reactive protein（CRP） of patients with acute exacerbation chronic obstructive pulmonary disease. Methods Forty-five cases of elderly patients with acute exacerbation chronic obstructive pulmonary disease were divided into a treatment group （23 cases） and control group （22 cases）, the patients of treatment group injected Chuankezhi within a muscle, each 4 ml,2 times a day, one week for a course of treatment. Blood gas analysis and serum CRP were determined before treatment, medication fourth day and after medication. Results In the treatment group, the PaO2 increased levels higher than that of the control group （ P〈0.05） and CRP level decreased significantly compared with the control group （ P〈0.05）. Conclusions Chuankezhi injection can significantly improve blood gas PaO2 and serum CRP levels of patients with acute exacerbation chronic obstructive pulmonary disease.