摘要
从虫类中药蛴螬Holotrichia diomphalia Bates的乙醇提取物中分离得到13个化合物,其结构经谱学数据和与已知化合物比较,分别鉴定为N-[2-(4-羟苯基)-乙基]乙酰胺(1)、环(酪氨酸-脯氨酸)(2)、吡啶-3-甲酰胺(3)、胸苷(4)、戊内酰胺(5)、5-(羟甲基)-1H-吡咯-2-醛(6)、环(脯氨酸-缬氨酸)(7)、环(脯氨酸-丙氨酸)(8)、羟吲哚(9)、1,2,3,4-四氢-1,3,4-三氧-β-咔啉(10)、吲哚-3-醛(11)、黄苷(12)和苯基丙氨酸(13)。化合物1~13均为首次从该种动物药中分离得到。
Thirteen nitrogenous compounds were isolated from the ethanol extract of a medicinal insect, namely Holotrichia diomphalia Bates. The thirteen compounds were identified as N- [ 2 - (4 -hydroxybenzoic) -ethyl] acetamide ( 1 ), cyclo ( Tyr-Pro ) (2), pyridine-3 -carboxylic acid amide ( 3 ), thymidine ( 4 ), valerolactam ( 5 ), 5 - ( hydroxraethyl ) -1H- pyrrole-2-carbaldehyde (6), cyclo(Pro-Val) (7), cyelo (Pro-Ala) ( 8 ), oxindole (9), 1,2,3,4-tetrahydro-1,3,4-trioxo-β-carboline (10), indole-3-aldehyde ( 11 ), xanthosine ( 12 ) and phenylalanine (13) using spectroscopic methods. All these compounds were isolated from this species for the first time.
出处
《天然产物研究与开发》
CAS
CSCD
北大核心
2013年第3期329-332,共4页
Natural Product Research and Development
基金
云南省科技强省中德国际合作项目(2009AC011)
关键词
虫药蛴螬
含氮化合物
二肽
核苷
酰胺
Holotrichia diomphalia
nitrogenous compounds
dipeptide
nucleoside
amide