胰岛素泵在结直肠癌合并2型糖尿病患者围手术期的应用

Application of Insulin Pump During Perioperation of the Patients with Colorectal Carcinoma Complicated with 2 Type Diabetes

为探讨结直肠癌合并2型糖尿病患者围手术期应用胰岛素泵控制血糖的效果，回顾2008年1月至2011年12月于我科接受手术治疗的68例结直肠癌合并2型糖尿病患者资料。其中36例通过胰岛素泵给予持续皮下输注胰岛素（观察组），32例予胰岛素多次皮下注射（对照组），对比观察两组患者空腹血糖、餐后2h血糖、待手术时间、术后感染情况。结果显示，两组患者血糖均得到有效控制；但观察组待手术时间明显短于对照组，P〈0．05；术后感染率及低血糖发生率均明显低于对照组，P〈0．05。结果表明，应用胰岛素泵控制结直肠癌合并2型糖尿病患者围手术期血糖安全有效，而且可以较快地达到降糖效果，缩短待手术时间，减少术后并发症，值得临床推广应用。

In order to explore the control blood glucose efficacy of insulin pump used at perioperation of the patients with colorectal carcinoma complicated with 2 type diabetes, authors retrospectively analyzed the data of 68 patients with this disease who had been subjected to surgery from Jan. 2008 to Dec. 2011 yr. in author＇s department among whom 36 patients were continuously infused with insulin subcutaneously through insulin pump（as observation group）,rest 32 with insulin subcutaneously through multiple time in- jection （as control group） ;the levels of fasting blood glucose and blood glucose at postprandial 2 hours,the time to wait operation and the status of postoperative infection in both groups were measured and ob- served, then compared and analyzed. As results, the blood glucose level of both groups were effectively con- trolled, but the time to wait operation of observation group was significantly shorter than that of control group（ P %0. 05）, postoperative infection rate and hypoglycemia occurence rate also lower than that of control group（ P %0.05）. Results show that for the patients of colorectal carcinoma complicated with 2 type diabetes using insulin pump to control the perioperative level of blood glucose is safe and effective,and more fastly can obtain outcome of lowering blood glucose level, so that shorten the time to wait operation, reduce postoperative complication,thus it is worthy to be popularized clinically.