离休老年患者铜绿假单胞菌感染及耐药性分析

Analysis on infection of Pseudomonas aeruginosa and its drug-resistance among retired cadres

目的探讨离休老年患者铜绿假单胞菌(PAE)感染及耐药性特点,为临床抗感染治疗和合理使用抗菌药物提供依据。方法回顾性分析我院2009年1月—2011年12月从患下呼吸道感染的综合科离休老年患者痰液中分离的259株PAE的感染原因及病原菌耐药性特点。结果离休老年患者医院感染发生率高,下呼吸道感染PAE在非发酵菌中位于首位,分离率逐年升高;对抗菌药物的耐药率上升明显,尤其是碳青霉烯类和复方β-内酰胺类抗生素最为显著。结论 PAE是老年患者呼吸道感染的主要病原菌,分离比例和耐药率呈上升趋势。

Objective To investigate the status of carrying Pseudomonas aeruginosa and its drug-resistance in retired cadres with respiratory tract infection, so as to provide a basis for clinical anti-infection treatment and rational use of antimicrobial drugs. Methods A total of 259 strains of Pseudomonas aeruginosa which were isolated from the elderly patients with respiratory tract infection during January 2009 and December 2011 were identified and analyzed the resistance. Results The nosocomial infection rate of the retired was high. The separation rate of Pseudomonas aeruginosa increased year by year. Antimicrobial resistance rate increased significantly, especially carbapenems and compound β-1actam antibiotics. Conclusion Pseudomonas aeruginosa is the main pathogens in respiratory tract infections for elderly patients.