超声造影对宫颈癌术前诊断的效果研究

Effect of contrast-enhanced ultrosonography on preoperative diagnosis of cervical cancer

目的探讨超声造影(CEUS)对宫颈癌的诊断及临床分期的价值。方法选取2008年5月—2012年5月于我院就诊的70例疑为宫颈癌的患者,经临床病理证实,宫颈癌45例,宫颈上皮内瘤变10例,正常15例,均进行普通超声和CEUS检查,分析其阴道超声图谱声像特征以及造影增强特征。结果宫颈癌CEUS可以清晰显示癌灶的范围,宫颈病变造影参数结果显示宫颈癌组早期增强时间以及峰值时间较短,其强度明显高于对照组和宫颈上皮瘤变组,且CEUS的符合率明显高于普通超声(US),差异均具有统计学意义(P<0.05)。结论经阴道CEUS技术不仅可以显著提高宫颈癌的临床诊断率,还可以明确宫颈癌的临床分期,对宫颈癌的早期诊断、治疗和预后都有重要的价值。

Objective To study the influence of contrast-enhanced ultrosonography （CEUS） on diagnosis of cervical cancer and its diagnostic value in clinical staging of cervical cancer. Methods A total of 70 patients suspected of cervical cancer in our hospital from May 2008 to May 2012 were enrolled in the study. By means of clinically pathological confirmation, cervical cancer was oceured in 45 and cervical intraepithelial neoplasia in 10 ones. The other 15 cases were healthy or normal. All the patients were examined by conventional uhrosonography and CEUS. Results CEUS clearly showed the extent of the lesions of cervical cancer. The parameters of CEUS showed that the early enhancement time and peak time of cervical cancer group were comparatively short and its enhancement intensity was obviously higher than both that of control group and that of cervical intraepithelial neoplasia group. The coincidence rate of CEUS was obviously higher than that of conventional uhrosonography. All the differences were statis- tically significant （ P 〈 0.05）. Conclusion Transvaginal CEUS can not only improve the rate of clinical diagnosis of cervical Cancer, but also definitude the clinical stage. It is of great value to the early diagnosis, treatment and prognosis of cervical cancer.