摘要
目的探讨FGR与孕妇血清中甲状腺素的关系。方法采用放射免疫分析法,测定正常足月妊娠38例(正常组)和足月妊娠FGR 22例(FGR组)孕妇血清中甲状腺素(T4)、三碘甲状腺原氨酸(T3)、游离T4(FT4)、游离T3(FT3)、促甲状腺素(TSH)水平,比较两组甲状腺素水平。结果 FGR组孕妇血清TSH高于对照组(P<0.01),T4、T3、FT4、FT3均低于对照组,其中T4、FT4差异有显著性意义(P<0.05)。结论 FGR的发病可能与甲状腺功能低下有关。
Objective: To investigate the relationship between fetal growth restriction(FGR) and thyroid hormone in maternal blood.Methods:22 termed pregnancies with FGR(FGR group) and 38 normal termed pregnancies(normal group) were studied.Maternal blood were collected from all the cases.The levels o f thyroxin(T4),triiodothyronine(T 3),free T4(FT4),free T3(FT3) and thyroid-stimulating hormone(TSH) were measured by immunoradiometric assay(IRMA)technique,and were compared between each group.Results:The TSH was higher in FGR group than that in the normal group(P0.01).The T4,FT4 was lower in FGRs group than that in the normal group(P0.05).Conclusions: This study confirmed the pathogenesis of FGR may be connected with the functional decay of thyroid.
出处
《中国优生与遗传杂志》
2013年第3期75-75,86,共2页
Chinese Journal of Birth Health & Heredity