盆炎净颗粒治疗慢性盆腔炎82例疗效及副反应观察

Penyanjing Granule Treat Chronic Pelvic Inflammation 82 Cases and Observation of Side Effects

[目的]观察盆炎净颗粒冲剂临床治疗慢性盆腔炎(Chronic pelvic inflammatory disease,CPID)中的疗效及副反应。[方法]依标准选取在我院2010年5月至2012年7月门诊并被诊断为CPID160病例,随机法并以两组具有可比性为前提,分为对照组78例(口服左氧氟沙星胶囊及甲硝唑片),治疗组82例(在服用对照组药物基础上加服盆炎净颗粒,均1疗程后观察体征、症状改善情况、总有效率及副反应。[结果]对下腹坠痛腰骶酸痛、白带增多、子宫活动受限压痛、输卵管条索状压痛4组主要体征、症状的总有效率分别为92.31%、87.93%、91.93%、81.25%,均优于对照组,前3组有统计学意义(P<0.05);治疗组总有效率为97.56%,优于对照组89.74%,有统计学意义(P<0.05);两组副反应比较,治疗组优势显著,统计学差异有显著性(P<0.01)。[结论]盆炎净颗粒冲剂治疗CPID临床疗效明确,副反应小,值得临床应用。

[Objective] To observe the cure effect and side effects of Penyanjing Granule treating chronic pelvic inflammation（CPI）.[Method] Select 160 of such cases,randomly divide them into control group（n =78） orally taking levofloxacin capsule and metronidazole tablets,and the treatment group taking Penyanjing Granule on the basis of control group;after 1 course,observe their signs,relieve of symptoms,total effective rate and side effects.[Result] The total effects of 4 symptoms of abdomen bearing-down pain and back-waist ache,leucorrhea increment,uterus LOM and tenderness,ovarian ducts streak tenderness were respectively 92.31%,87.93%,91.93% and 81.25% in treatment group,all better than control one;the first 3 had statistical meaning;the total effective rate was 97.56% in treatment group,better than control one 89.74%,their difference was of statistical meaning;on comparison of side effects,the treatment group had marked advantages with statistical meaning.[Conclusion] Penyanjing Granule infusion has definite cure effect on CPI,with little side effects,worthy clinical application.