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RANKL/RANK/OPG系统生物学功能的研究进展

Research Progress on Biological Function of RANKL/RANK/OPG System
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摘要 RANKL(Receptor activator of nuclear factor￣κB ligand)/RANK/OPG系统在骨吸收调节中可识别调节细胞功能的因子。RANKL/OPG比例是决定骨量和骨密度的重要因素。虽然对它们调节破骨细胞形成的作用机制已有十多年的研究,但它们在健康和病理条件下的作用还存在着许多问题。现就RANKL/RANK/OPG系统在骨代谢中的作用做一总结。 Regulation factor of cell function was identified in bone resorption by RANKL/RANK/OPG system.RANKL/OPG ratio is an important factor to determine bone mass and bone mineral density.Although the mechanism of regulate osteoclast formation was researched for more than ten years, the role in healthy and pathological conditions also existed many problems. The role of RANKL/RANK/OPG system in bone metabolism was summerized in the article.
作者 赵剑
机构地区 天津市口腔医院牙体牙髓病一科
出处 《现代诊断与治疗》 CAS 2013年第1期82-84,共3页 Modern Diagnosis and Treatment
关键词 破骨细胞 RANKL RANK OPG Osteoclasts RANKL RANK OPG
分类号 Q81 [生物学—生物工程]
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参考文献20

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二级参考文献64

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现代诊断与治疗
2013年 第1期

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