原发性骨髓纤维化转急性髓系白血病M6一例并文献复习
被引量：1
摘要
目的 探讨罕见的原发性骨髓纤维化（PMF）转化为急性髓系白血病（AML）M6的疾病进展过程，对其机制及目前的临床治疗进行探讨并复习文献。方法 回顾性分析1例PMF转AML-M6患者转化前后的临床资料。结果 患者转白血病前后JAK2 V617F基因突变均为阴性，转化后新出现了＋8和del（X）（q22）染色体异常。患者从诊断为PMF到转化为白血病的时间为16个月。结论 PMF转化为AML-M6罕见，患者临床预后差，生存期短。
出处
《白血病．淋巴瘤》
CAS
2013年第3期176-178,共3页
Journal of Leukemia & Lymphoma
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