肺癌患者首次化疗前后心理状况及生活质量研究

Research on psychological status and quality of life in patients with lung cancer before and after first round of chemotherapy

目的探讨肺癌患者化疗前后的心理状况、生存质量及其相关性。方法收集2010年1月至2012年10月收治并行化疗的110例肺癌患者,采用医院用焦虑抑郁量表(HADS)和患者生存质量测定量表体系—肺癌量表(WLICP-LU)对患者化疗前后心理状况及生活质量进行评价,比较化疗前后肺癌患者的心理状况与生活质量的相关性。结果 (1)化疗后患者心理状况评分、生活质量总分均与化疗前存在明显差异(11.21±3.98和15.10±3.31)、(145.98±14.22和161.07±18.52),且差异有统计学意义(P<0.05);(2)化疗前后患者心理得分与其生活质量评分之间呈负相关(P<0.05)。结论肺癌患者化疗后心理状况好于化疗前,生活质量也高于化疗前。化疗患者心理状况越好,生活质量越高,二者呈明显的相关性。

Objective To investigate psychological status and quality of life in patients with lung cancer before and after first round of chemotherapy and its correlation.Methods 110 admitted lung cancer patients from January 2010 to October 2012 were selected as study objects,and hospital anxiety and depression scale（HADS） quality of life instruments for cancer patients lung cancer（QLICP-LU） were applied to evaluate patients＇ psychological status and quality of life,then differences of psychological status score and survival quality score were noted and compared before and after first round of chemotherapy.Results ①After chemotherapy,the patients＇ psychological status score,life quality scores were obviously distinct from pre-chemotherapy（11.21±3.98 and 15.10±3.31）、（145.98±14.22 and 161.07±18.52）,and the difference with statistical significance（P0.05）.②Patients＇ psychological status score before and after chemotherapy were negatively correlated with life quality scores（P0.05）.Conclusions Lung cancer patients whose psychological condition and quality of life are superior than prior reatment,and psychological score is more higher,survival quality is more better.