围生儿出生缺陷123例监测结果分析

Analysis of monitoring results in 123 cases of perinatal birth defects

目的通过对2007—2012年123例出生缺陷儿的分析,为临床预防和治疗、有效降低出生缺陷发生率提供依据。方法对2007—2012年分娩的围产儿及出生缺陷儿,进行监测统计和分析。结果出生缺陷类型前4位是肢体畸形、唇腭裂、尿道下裂、胎儿水肿综合征,其发生率分别为30.9%、19.5%、13.0%、12.2%。乡村地区发生率明显较城镇高。结论加强婚前检查,普及优生优育知识,特别是边远山区乡村人群,进行孕早期保健是预防出生缺陷的关键,加强对高危妊娠的检测和产前筛查,达到及早干预,是降低围产儿出生缺陷率的重要手段。

Objective To analyze 123 cases of birth defects during 2007—2012 to provide the basis for clinical prevention and treatment,and effectively reducing the occurrence rate of birth defects.Methods Perinatal infants and birth defects delivered during 2007—2012 were performed monitoring and statistic analysis.Rsults The top 4 birth defects were limb deformity,cleft lip and palate,hypospadia and fetal edema.Their incidence rates were 30.9%,19.5%,13.0% and 12.2%.The incidence rate in rural areas was significantly higher than that in cities and towns.Conclusion Strengthening the pre-marital check,popularizing prenatal and postnatal care knowledge,especially in the remote mountain village population,conducting early pregnancy care are the key to prevent birth defects.Strengthening the detection of high-risk pregnancy and prenatal screening and adopting early intervention are the important means to reduce the rate of birth defects in perinatal infants.