老年慢性阻塞性肺疾病患者认知功能障碍调查

The investigation on the cognitive state of elder patients with chronic obstructive pulmonary disease

目的评估老年慢性阻塞性肺疾病(COPD)认知功能状况。方法采用简明精神量表(mini-mental stateexamination,MMSE)及蒙特利尔认知评估量表(Montreal cognitive assessment,MoCA)量表对2010年1月～2012年8月解放军总医院门诊及住院患者120例COPD患者进行认知功能评估,并进行一般情况问卷调查。COPD依病情严重程度分为Ⅰ～Ⅳ级,并对病情程度与认知功能情况进行受试者工作特征曲线(receiver operating curve,ROC)分析。采用SPSS 18.0软件进行统计学分析。结果 64例COPD患者认知功能正常,56例患者诊断为轻度认知功能障碍(MCI)。病程与MCI组患者MoCA评分呈负相关(r=-0.86,P<0.05)。受试者工作特征曲线(ROC)分析提示曲线下面积为0.822。结论 COPD患者可以伴发认知功能损害,要注重早期心理护理。

Objective To investigate the cognitive state in elder patients with chronic obstructive pulmonary disease（COPD）.Methods Mini-mental state examination（MMSE） and Montreal cognitive assessment（MoCA） were applied to 120 COPD patients from January 2010 to August 2012 in outpatient and inpatient of General Hospital of Chinese PLA and general medical history was evaluated.The patients with COPD was classified into grade Ⅰ-Ⅳ based on the patient＇s condition.Receiver operating curve（ROC） was applied for the statistics.Statistical analysis was performed using SPSS 18.0 software.Results 64 patients were in normal cognitive state,and 56 patients were diagnosed as mild cognitive impairment（MCI）.The disease duration showed a negative correlation with MoCA scores（r =-0.86,P 0.05）. Receiver operating curve analysis demonstrated that the area of under the curve was 0.822.Conclusion COPD patients could be concomitant with MCI,and early mental nursing should be applied.