心理干预对产妇焦虑症状影响的Meta分析

Influence of psychological intervention on puerpera anxiety: a meta-analysis

目的采用循证医学Meta分析的方法以探讨心理干预对产妇焦虑症状的影响。方法计算机检索万方、VIP、CNKI、CBM、Pubmed、Embase、Cochrane图书馆等中英文数据库,全面收集有关心理干预对产妇焦虑症状影响的临床对照试验,汇总数据采用RevMan 5.1.6和Stata 12.0进行分析,两组之间差异采用标准均数差(stan-dardized mean difference,SMD)或优势比(OR)及其95%可信区间(95%confidence interval,95%CI)描述。结果严格根据纳入和排除标准,最终纳入6个临床对照试验,包括383例干预产妇和384例对照组。Meta分析结果表明:治疗前,心理干预组与对照组产妇焦虑状况SAS评分无明显差异(SMD=-0.15,95%CI=-1.44～1.13,P=0.82);治疗后,心理干预组产妇焦虑症状SAS评分显著低于对照组患者,差异有统计学意义(SMD=-11.07,95%CI=-15.68～-6.46,P<0.000 1)。结论心理干预可有效地改善产妇的焦虑症状,对产妇的身心健康和婴儿健康成长有积极作用。

Objective To investigate the influence of psychological intervention on puerpera anxiety by conducted a systematic review and meta-analysis. Methods Wan Fang, VIP, CNKI, CMB, Pubmed, Embase, Cochrane databases were searched extensively to identify relevant clinical controlled trials. Data were analyzed by RevMan 5.1.6 and Stata 12.0 softwares. Results were described as standardized mean difference （SMD） with 95% confidence intervals （CI）. Results Finally, a total of 6 clinical controlled trials involving were included in this systematic review, including 383 patients in the observation group and 384 puerpera in the control group. Meta-analysis showed that pre-intervention there were no significant difference between two groups on SAS scores （SMD= -0.15, 95%C1= -1.44-1.13,P = 0.82）. While, post-intervention two groups SAS scores （SMD= -0.15, 95%CI= -1.44-1.13 ,P = 0.82; SMD= -11.07, 95%CI= -15.68- -6.46, P 〈 0.000 l） had statistically significant differences. Conclusion The present data suggests that psychological intervention may relieve anxiety symptoms for puerpera. Further well-designed randomized con- trolled trials are needed to confirm or adjust current conclusions.