米非司酮配伍米索前列醇用于终止12～16周妊娠的临床观察

Clinical observation of mifepristone and misoprostol for terminating 12-16 weeks' gestation

目的观察米非司酮配伍米索前列醇用于终止12～16周妊娠的临床效果。方法将210例孕12～16周要求终止妊娠的妇女依处理方式不同分成观察组和对照组各105例。观察组采用米非司酮配伍米索前列醇,对照组采用依沙吖啶羊膜腔内注射。观察两组患者有效率、阴道流血量。结果与对照组相比,观察组患者引产有效率显著,流产时间较短,两组差异有统计学意义(P<0.05)。结论米非司酮配伍米索前列醇用于终止12～16周妊娠具有良好的临床效果。

Objective To observe the clinical effect of mifepristone and misoprostol for terminating 12 to 16 weeks＇ pregnancy. Methods Selected 210 cases of women who requested to terminate 12 to 16 weeks pregnancy, randomly di- vided them into two groups, the observation group and control group, each group had an average of 105 cases, the ob- servation group patients were treated with Mifepristone with Misoprostol, and the control group patients were treated with ethacridine intra-amniotic injection . Then observed the two groups patients＇ amount of vaginal bleeding careful- ly. Results Compared with the control group, the observation group patients＇ induction labor efficiency was higher and abortion time was shorter, the difference was statistically significant （P 〈 0.05）. Conclusion Mifepristone and misoprostol has good clinical results for terminating 12 to 16 weeks＇ gestation.