C反应蛋白对小儿急性呼吸道感染的意义

The significance of C reactive protein for diagnosis of transmissibility pneumonia

目的探讨C反应蛋白(CRP)检测在小儿急性呼吸道感染中的临床价值。方法选择呼吸道感染患儿203例作为观察组和健康儿童80例作为对照组,分别测定其血清CRP水平和白细胞总数(WBC)。结果细菌性肺炎的CRP值(F=346.83,P<0.01)、CRP阳性率(χ2=241.36,P<0.01)和WBC(F=952.88,P<0.01)、WBC阳性率(χ2=186.27,P<0.01)均高于病毒性肺炎和对照组,差异有统计学意义;而病毒性肺炎和对照组比较差异无统计学意义。细菌性肺炎治疗前后CRP(χ2=188.70,P<0.01)、WBC阳性率(χ2=180.14,P<0.01)明显降低,差异有统计学意义(P<0.05)。结论血清CRP水平在小儿肺炎的鉴别诊断中具有重要的临床意义。

Objective To explore the clinical significance of c-reactive protein （CRP） in the pediatric pneumonia. Methods All of 203 children with pneumonia in hospitalized patients were selected as study group, 80 healthy chil- dren as control group, CRP and WBC were recorded. Results The CRP （F = 346.83, P 〈 0.01 ）, the positive rate of CRP（x2=241.36, P 〈 0.01 ）, the number of WBC（F = 952.88, P 〈 0.01） and the positive rate of WBC（x2=186.27, P 〈 0.01 ） in bacterial infection group increased significantly compared with viral infection group and normal control group（P 〈 0.01 ）, while there were no significant differences between the viral pneumonia group and the control group. The positive rates of CRP （x2=188.70, P 〈 0.01）and WBC （X2=180.14, P 〈 0.01） were significantly different between pre-and post-treatment in bacterial infection group. Conclusion Serum CRP level has important clinical significant in diagnosis of pneumonia in children.