摘要
目的探讨冠状动脉靶病变钙化与相关因素的关系。方法 50例确诊为冠心病患者,其中男30例,女20例,采用血管内超声虚拟组织学成像(IVUS-VH)测量冠脉靶病变钙化负荷,结合相关因素,采用多元回归分析寻找相关性。结果冠状动脉靶病变钙化与尿酸(P<0.01)、碱性磷酸酶(P<0.01)、骨结合蛋白(P=0.027)呈正相关性,与骨保护素(r=-1.1229,P=0.0242)呈负相关。结论尿酸、碱性磷酸酶等因素可能影响冠脉钙化。
Objective TO assess calcification of target lesion in interventional therapy. Methods A total of 50 CHD patients were recruited, calcification burden in coronary artery were examined by IVUS-VH. The patients' clinical da- ta and serum indictors were detected and analyzed. Results Coronary calcification is positively related to serum uric acid (P 〈 0.01) Alkaline phosphatase(P 〈 0.01 ),bone morphogenetie protein(P =0.027), negatively related to osteo- protegerin (r = -1.1229, P = 0.0242). Conclusion Improve lifestyles and control blood pressure can impact coronary calcification.
出处
《中国现代医生》
2013年第7期145-146,148,共3页
China Modern Doctor
关键词
血管内超声虚拟组织学成像
冠状动脉钙化
Intravascular ultrasound virtual histology (IVUS-VH)
Coronary calcification