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从分子水平上寻求防治早产儿视网膜病变的方法 被引量：1

Methods for Prevention and Treatment of Retinopathy of Prematurity at the Molecular Level
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摘要 早产儿视网膜病变（ retinopathy of prematurity, ROP）是早产的严重并发症，不同国家其致盲率不同。在发展中国家，尤其是中国和印度，随着新生儿护理及NICU医疗水平的提高，极低出生体重儿存活率逐渐升高，
作者 唐烁 包蕾
机构地区 重庆医科大学附属儿童医院
出处 《儿科药学杂志》 CAS 2013年第4期56-59,共4页 Journal of Pediatric Pharmacy
关键词 早产儿视网膜病变 分子水平 极低出生体重儿 发展中国家 防治 严重并发症 新生儿护理 医疗水平
分类号 R774.1 [医药卫生—眼科]
  • 相关文献

参考文献27

  • 1Gilbert C, Fielder A, GordiUo L, et al. Characteristics of infants with severe retinopathy of prematurity in countries with low,moderate, and high levels of development: implications for screening programs [ J ]. Pediatrics, 2005, 115 (5) : 518-525.
  • 2Laser ROP Study Group. Laser therapy for retinopathy of prematurity [J]. Arch Ophthalmol, 1994, 112(2) : 154-156.
  • 3Chen J, Smith LE. Retinopathy of prematurity [ J ]. Angiogenesis, 2007, 10(2): 133-140.
  • 4Fleck BW, Mclntosh N. Pathogenesis of retinopathy of prematurity and possible preventive strategies [ J]. Early Hum Dev, 2008, 84 ( 2 ) : 83-88.
  • 5Nonobe NI, Kachi S, Kondo M, et al. Concentration of vascular endothelial growth factor in aqueous humor of eyes with advanced retinopathy of prematurity before and after intravitreal injection of bevacizumab [J]. Retina, 2009, 29(5) : 579-585.
  • 6Kong L, Mintz-Hittner HA, Penland RL, et aL Intravitreous bevacizumab as anti-vascular endothelial growth factor therapy for retinopathy of prematurity: a morphologic study [ J ]. Arch Ophthalmol, 2008, 126(8): 1161-1163.
  • 7张娟,张淑丽,王朝虹,李松,王新利.胰岛素样生长因子Ⅰ启动子区域基因多态性与新生儿血清IGF-Ⅰ水平的关系[J].中国新生儿科杂志,2007,22(5):264-267. 被引量：9
  • 8Hellstrom A, Engstrom E, Hard AL, et al. Postnatal serum insulin-like growth factor I deficiency is associated with retinopathy of prematurity and other complications of premature birth [ J ]. Pediatrics, 2003, 112(5) : 1016-1020.
  • 9Lofqvist C, Andersson E, Sigurdsson J, et al. Longitudinal postnatal weight and insulin-like growth factor I measurements in the prediction of retinopathy of prematurity [ J ]. Arch Ophthalmol, 2006, 124(12): 1711-1718.
  • 10Lofqvist C, Chen J, Connor KM, et al. IGFBP3 suppresses retinopathy through suppression of oxygen-induced vessel loss and promotion of vascular regrowth [ J ]. Proc Natl Acad Sci USA, 2007, 104(25): 10589-10594.

二级参考文献8

  • 1李利,张云,崔庆华,吴莉,董旭东,焦存仙.不同胎龄儿脐血IGF-1、IGFBP-1及CP水平的变化[J].新生儿科杂志,2004,19(6):252-254. 被引量：2
  • 2Allen NE,Davey GK,Key TJ,et al.Serum insulin-like growth factor Ⅰconcentration in men is not associated with the cytosineadenosine repeat polymorphism of the IGF-gene.Cancer epidemiol Biomarkers Prev,2002,11:319-320.
  • 3Klauwer D,Blum WF,Hanitsih S,et al.IGF-Ⅰ,IGF-Ⅱ,free IGF-Ⅰ and IGFBP-1,-2 and -3 levels in venous cord blood:relationship to birth weight,length and gestational age in healthy newborns.J Acta Paediatr,1997,86:826-833.
  • 4Vaessen N,Heutink P,Janssen JA,et al.A polymorphism in the gene for IGF-Ⅰ:functional properties and risk for type 2 diabetes and myocardial infarction.Diabetes,2001,50:637-642.
  • 5Arends N,Johnston L,Hokken-Koelega A,et al.Polymorphism in the IGF-Ⅰ gene:clinical relevance for short children born small for gestational age (SGA).J Clin Endocrinol Metab,2002,87:2720-2725.
  • 6Kinoshita Y,Kizaki Z,Ishihara Y,et al.The Relationship in Japanese infants between a genetic polymorphism in the promoter region of the insulin-like growth factorⅠgene and the plasma level.Neonatology,2007,92:116-119.
  • 7龚鹏,杨效文,张孝羲,刘向东,陈晓峰.棉蚜(Aphis gossypii)种群寄主分化和季节分化的微卫星引物PCR研究[J].生态学报,2001,21(5):765-771. 被引量：37
  • 8丁晓春,冯星.生长激素及胰岛素样生长因子-Ⅰ对新生儿生长发育调控的观察[J].中国实用儿科杂志,2003,18(7):402-404. 被引量：16

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儿科药学杂志
2013年 第4期

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