不同机械通气模式对COPD呼吸衰竭患者肺功能及氧代谢的影响比较

Comparison of influence of different mechanical ventilation modes on pulmonary function and oxygen metabolism of COPD patients complicated with respiratory failure

目的比较不同机械通气模式对COPD呼吸衰竭患者肺功能及氧代谢的影响。方法选取本院进行治疗的64例COPD呼吸衰竭患者为研究对象,将其随机分为A组和B组各32例,其中A组采用BiPAP模式进行干预治疗,B组则采用SIMV+PSV模式进行干预治疗,将两组治疗前及治疗后3 d、7 d的肺功能、血气分析及氧代谢指标进行比较。结果 B组治疗后3 d、7 d的肺功能、血气分析及氧代谢指标改善幅度均大于A组,P均<0.05,有显著性差异。结论 SIMV+PSV模式可显著改善COPD呼吸衰竭患者肺功能及氧代谢指标,对于改善患者呼吸衰竭的状态发挥着积极的作用。

Objective To compare the influence of different mechanical ventilation modes on pulmonary function and oxygen metabolism of COPD patients complicated with respiratory failure.Methods 64 COPD patients complicated with respiratory failure were randomly divided into the group A and the group B with 32 cases in each group.The group A were intervened with BiPAP mode,and the group B were intervened with SIMV＋PSV mode.Then the pulmonary function,blood gas analysis and oxygen metabolism indexes were compared between the two groups before and 3 days and 7 days after the treatment.Results The improvement of pulmonary function,blood gas analysis and oxygen metabolism indexes was more pronounced in the group B than in the group A（P0.05）.Conclusion The SIMV＋PSV mode can significantly improve the pulmonary function and oxygen metabolism indexes of COPD patients complicated with respiratory failure,as well as improve the situation of respiratory failure.