脂肪因子在Roux—en-Y胃旁路术治疗2型糖尿病中的研究进展

Progress of adipokines in the treatment of type 2 diabetes by the Roux-en-Y bariatric surgery

脂肪因子是脂肪组织分泌的一类活性物质，具有调节人体内血糖平衡等功能。实验证明，Roux—en-Y胃旁路术治疗2型糖尿病后，血浆中脂肪因子的水平会发生改变，其在改善胰岛功能方面具有重要作用。本文就脂肪因子作用途径及Roux—en—Y胃旁路术术后血浆中脂肪因子的水平变化等方面作一综述，以进一步探求手术治疗糖尿病的机制。

The adipokines is a class of active substances secreted by adipose tissue, with the function of regulating the body glucose balance and others. Some experiments prove Roux-en-Y gastric bypass postoperative plasma levels of adipokines will change that play an important role in improving islet function in the treatment of type 2 diabetes mellitus. Here, the author will make a review about the adipokines role in pathways and postoperative level changes, etc, in order to further explore the mechanism of the surgical treatment of diabetes.