前列腺增生患者肾功能损害与膀胱残余尿的相关性临床研究

Clinical study on the relationship between bladder residual urine volume and renal function lesion in benign prostatic hyperplasia patients

目的探索前列腺增生(BPH)患者肾功能损害与膀胱残余尿相关性。方法回顾性分析接受手术治疗并经病理证实为单纯BPH的病例441例,分成A组138例(残余尿量<12 mL),B组127例(残余尿量12～50 mL),C组51例(残余尿量50～200 mL),D组126例(残余尿>200 mL)。对四组患者的血肌酐、残余尿作对照研究。结果 A、B、C、D组的血肌酐分别为(98.23±42.00)μmol/L、(121.39±82.93)μmol/L、(67.15±24.78)μmol/L和(156.15±146.38)μmol/L,差异均有统计学意义。结论随着膀胱残余尿量的增多,BPH患者肾功能损害有加重趋势。

Objective To study the relationship between bladder residual urine volume and renal function lesion in patients with benign prostatic hyperplasia（BPH）. Methods Clinical data of 441 BPH were studied retrospectively. All the eases were divided into 4 groups：group A（ 138 cases, the residual urine volume 〈 12 ml） ,group B （127 cases ,the residual urine volume 12 -50 ml）, group C （50 cases, the residual urine volumeS0-200 ml） ,and group D（ 126 cases,the residual urine volume 〉 200 ml）. Blood serum creatinine （Cr） and urea niteogen（BUN） were observed and compared among the four groups. Results The serum Cr in group A, group B, group C, and group D were （ 98.23 ± 42. 00 ） μmol/L, （ 121.39 ± 82.93 ） μmol/L, （67.15 ± 24.78）μmol/L, and （ 156.15 ± 146.38 ）μmol/L, respectively. There existed statistical significant difference among all four groups. Conclusion Renal function impairment worsens with the increase of bladder residual urine volume in patients with BPH.