地榆炭化学成分研究

Chemical constituents from charred Sanguisorbae Radix

目的对地榆炭进行化学成分研究。方法采用色谱技术进行分离纯化,通过理化常数和波谱分析鉴定化合物结构。结果从地榆炭共分离得到5个化合物,分别鉴定为3β-羟基-28-去甲乌索-17,19,21-三烯(1)、3β-羟基-28-去甲乌索-12,17-二烯(2)、3β-O-α-L-阿拉伯呋喃糖基-28-去甲乌索-12,17-二烯(3)、3β-O-α-L-阿拉伯吡喃糖基-28-去甲乌索-12,17-二烯(4)和坡模酸(5)。结论化合物1、3和4为首次发现的三萜及其皂苷类新化合物,分别命名为地榆皂苷元Z、地榆皂苷Y1和地榆皂苷Y2。

Objective To study the chemical constituents from charred Sanguisorbae Radix. Methods The compounds were isolated and purified by column chromatography and their structures were identified on the basis of physicochemical properties and spectral analysis. Results Five compounds were isolated and identified as 3β-hydroxy-28-norurs-17, 19, 21-trien （1）, 313-hydroxy-28- norurs- 12, 17-dien （2）, 313-[（α-L-arabinofuranosyl） oxy]-28-norurs- 12, 17-dien 3β-, 19a-dihydroxyurs- 13（18）-en-28-oic acid （3）, 3β- [（ct-L-arabinopyranosyl）oxy]-28-norurs-12, 17-dien （4）, and pomolic acid （5）. Conclusion The compounds 1, 3, and 4 are novel compounds which belong to triterpenoids and triterpenoid saponins, named sanguisorbigenin Z, sanguisorbin Y1, and sanguisorbin Y2, respectively.