干预前后骨科Ⅰ类切口手术围术期预防性应用抗菌药物对比分析

Contrastive Analysis of The Perioperative Use of Antibiotics in Patients Undergoing Type Ⅰ Incision Orthopedic Surgery before and after The Intervention

目的:调查实施药学服务和行政干预后围术期预防性应用抗菌药物的合理性情况,推动医院合理用药工作的开展。方法:选取骨科Ⅰ类切口手术2011年3—7月出院病历为干预前组、2012年3—7月出院病历为干预后组,对比分析干预前后围术期预防性应用抗菌药物的合理性。结果:抗菌药物预防性使用率由干预前的93%下降为干预后的67.1%(P<0.01),术前抗菌药物预防性应用时间不当由干预前的63.01%下降为干预后的27%(P<0.01)。实施药学服务和行政干预后,各项不合理用药情况有不同程度的改善。结论:实施围术期预防性应用抗菌药物干预措施是有效的,应进一步优化各项措施,以促进临床合理用药。

OBJECTIVE：To investigate the rationality in perioperative use of prophylactic antibiotics in patients undergoing type Ⅰ incision orthopedic surgery after carrying out pharmaceutical care and administrative intervention in order to promote rational drug use work in hospital.METHODS： The medical records of patients undergoing type I incision orthopedic surgery who were discharged during Mar.-Jul.period of 2011（before intervention） vs.discharged during Mar.-Jul.period of 2012（after intervention） were analyzed contrastively with regard to the rationality of perioperative use of prophylactic antibiotics before and after intervention.RESULTS： The rate of antibiotic use has been decreased from 93% before intervention to 67.1% after intervention（P0.01） and the rate of improper administration time of antibiotics has been decreased from 63.01% before intervention to 27% after intervention（P0.01）.Moreover,all the irrational drug use phenomena have been improved to some degree after carrying out pharmaceutical care and administrative intervention.CONCLUSION： The intervention measures on perioperative use of prophylactic antibiotics in patients undergoing type Ⅰ incision orthopedic surgery is proved to be effective.The intervention measures remain to be further optimized to promote clinical rational drug use.