摘要
目的:分析药品不良反应(ADR)发生的特点及临床表现,为临床合理用药提供参考。方法:利用Excel电子表格对2008—2012年我院收集上报的136例ADR报告中患者的性别、年龄、涉及药物类别、给药途径、ADR累及器官和(或)系统进行统计分析。结果:136例ADR中,抗菌药物引起ADR最为多见,有66例次,占48.53%,其次为中药注射剂55例次,占40.44%;给药途径方面,静脉给药致ADR为130例,占95.59%;ADR累及器官和(或)系统主要为神经系统(75例次,占37.88%)、皮肤及其附件(51例次,占25.76%)。结论:应严格按照《抗菌药物临床应用指导原则》合理使用抗菌药物,规范中药注射剂的临床应用,保障患者用药安全、有效。
OBJECTIVE：To analyze the characteristics and clinical manifestation of the adverse drug reactions （ADRs） occurred in our hospital so as to provide reference for clinical rational drug use. METHODS： Using Excel spreadsheet, 136 ADR cases reported by our hospital during 2008-2012 were analyzed statistically with regard to patients＇ age and sex, the drug categories involved, route of administration, and organ and （or systems） involved. RESULTS： Of all the drugs induced the 136 ADR cases, antibacterial drugs took the lead with 66 cases （48.53%） , followed by traditional Chinese medicine injection with 55 cases （40.44%）. Regarding the route of administration, 130 （95.59%） were induced by intravenous route. Regarding the organs and or （systems） involved, nervous system lesions took the lead with 75 （37.88%） followed by lesions of skin and its accessories with 51 （25.76%）. CONCLUSION： The antibacterials should be used rationally by strictly follow the Guiding Principle of Clinical Application of Antibacterial Drugs order to ensure patients＇ safe and . It is urgent to standardize he clinical application of Chinese medicine injections in effective medication.
出处
《中国医院用药评价与分析》
2013年第3期263-265,共3页
Evaluation and Analysis of Drug-use in Hospitals of China
关键词
药品不良反应
抗菌药物
中药注射剂
合理用药
Adverse drug reaction
Antibacterials
Traditional Chinese medicine injection
Rational drug use
