糖尿病并发急性胰腺炎38例临床分析

目的:探讨探讨糖尿病并发急性胰腺炎的病因、诊断及治疗效果,提高临床诊治水平。方法:收治糖尿病并发急性胰腺炎患者38例,均检测随机血糖、血尿淀粉酶。及时给与胰岛素治疗和乌司他汀10万U,溶于10%葡萄糖250ml静滴,1次/12小时,奥曲肽治疗,0.6mg/24小时持续静滴,连用5～7天,根据临床需要,需要时进行手术治疗。结果:治疗前血糖12.33±6.88mmol/L,血淀粉酶1080±320U/L,尿淀粉酶2460±456U/L,治疗后血糖7.36±2.13mmol/L,血淀粉酶310±205U/L,尿淀粉酶550±320U/L,治疗前后比较差异有显著性(P<0.05)。结论:糖尿病并发急性胰腺炎死亡率高,时用胰岛素治疗,可以减少术后感染,减少术后死亡率。

Objective：To investigate the etiol- ogy, diagnosis, and treatment effects of dia- betes complicated by acute pancreatitis and improve the level of clinical diagnosis and treatment. Method：collected in our hospital from January 2010 to November 2012, the treatment of 38 patients with diabetes and a- cute pancreatitis patients, detect random blood sugar, urine amylase. Timely to give insulin therapy and ulinastat, 100000 U, was dissolved in 10% glucose 250ml intra- venous infusion, 1/12 hours, octreotide treat- ment, 0. 6mg/24 hour continuous intrave- nous infusion, once every 5 to 7 days, ac- cording to clinical need, the need for surgi- cal treatment. Results ： Before treatment, blood glucose 12.33 ± 6.88retool/L, serum amylase 1080 ± 320U/L, urine amylase 2460 ± 456U/L after treatment, blood glu- cose 7.36 ± 2. 13mmol/L, serum amylase 310 ± 205U/L, urine amylase 550± 320u/ L, before and after treatment were significantdifferences（ P 〈 O. 05 ）. Conclusion ： diabetes and acute pancreatitis high mortality when treated with insulin, can reduce postopera- tive infection, reduce postoperative mortali- ty.