甲状腺乳头状癌BRAF突变与RET/PTC重排的临床意义
摘要
甲状腺癌是内分泌系统最常见的恶性肿瘤，也是近30年来发生率增长最快的实体肿瘤，每年增加6．2％。
出处
《医学研究杂志》
2013年第3期189-192,共4页
Journal of Medical Research
基金
浙江省医药卫生科学研究基金资助项目(2010KYA161)
参考文献18
-
1Cramer JD, Fu P, Harth KC, et al. Analysis of the rising incidence of thyroid cancer using the Surveillance, epidemiology and end results national cancer data registry[ J ]. Surgery ,2010,148 ( 6 ) : 1147 - 1152.
-
2Tang KT, Lee CH. BRAF mutation in papillary thyroid carcinoma: pathogenic role and clinical implications [ J ]. J Chin Med Assoc, 2010,73(3) :113 - 128.
-
3Henderson YC, Shellenberger TD, Williams MD, et al. High rate of BRAF and RET/PTC dual mutations associated with recurrent papilla- ry thyroid carcinoma[ J . Clin Cancer Res,2009,15 (2) :485 - 491.
-
4Zafon C, Obiols G. The mitogen- activated protein kinase (MAPK) signaling pathway in papillary thyroid cancer. From the molecular ba- ses to clinical practice[ J]. Endocrinol Nutr,2009,56 (4) :176 - 186.
-
5Stanojevic B, Dzodic R, Saenko V, et al. Mutational and clinico - pathological analysis of papillary thyroid carcinoma in Serbia[J]. En- docr J,2011,58(5) :381 -393.
-
6Nikiforov YE, Ohori NP, Hodak SP, et al, Impact of mutational tes- ting on the diagnosis and management of patients with cytologically in- determinate thyroid nodules : a prospective analysis of 1056 FNA sam- pies[ J. J Clin Endocrinol Metab,2011,96 ( 11 ) :3390 - 3397.
-
7Nikiforova MN, Nikiforov YE. Molecular diagnostics and predictors in thyroid cancer[J]. Thyroid,2009,19 (12) : 1351 - 1361.
-
8Maria RP, Isabella MB, Susi B, et al. BRAF analysis by fine needle aspiration biopsy of thyroid nodules improves preoperative identifica- tion of papillary thyroid carcinoma and represents a prognostic factor [ J]. A mono -institutional Experience Clin Chem Lab Med ,2011,49 (2) :325 -329.
-
9Anna G, Maria RS, Vincenzo M, et al. Prevalence of RET/PTC rear- rangement in benign and malignant thyroid nodules and its clinical ap- plication[J]. EndoJ,2011,58 (1):31-38.
-
10Kang DY, Kim KH, Kim JM, et al. High prevalence of RET, RAS, and ERK expression in Hashimoto's thyroiditis and in papillary thyroid carcinoma in the Korean population [ J ]. Thyroid, 2007,17 ( 11 ) : 1031 - 1038.
-
1王萍,赵世华,王颜刚.RET原癌基因与甲状腺乳头状癌的研究进展[J].医学综述,2008,14(6):854-856.
-
2朱晓丽,朱雄增.原癌基因RET与甲状腺乳头状癌关系的研究进展[J].中华病理学杂志,2004,33(4):374-377. 被引量：4
-
3王萍,王颜刚,赵文娟,付浴东,王娈,王芳,赵世华.甲状腺乳头状癌BRAF基因突变及RET／PTC基因重排与血小板源性生长因子B表达的相关性研究[J].中华内科杂志,2012,51(12):987-992. 被引量：7
-
4王文兰,王萍,赵世华,林东亮,赵诚,王颜刚,王斐.BRAF^(T1799A)突变、RET/PTC重排对术前诊断甲状腺乳头状癌的作用[J].现代生物医学进展,2015,15(16):3028-3033. 被引量：8
-
5王玉龙,王久存,李端树,朱永学,吴毅,嵇庆海.甲状腺乳头状癌的基因重排分析[J].中华耳鼻咽喉头颈外科杂志,2007,42(12):929-933. 被引量：3
-
6李田军,林岩松,梁军,李方.分化型甲状腺癌相关基因的研究进展[J].中华肿瘤防治杂志,2011,18(11):896-900. 被引量：13
-
7张蓉,李连喜.乳头状甲状腺癌与相关基因DNA甲基化[J].国际内分泌代谢杂志,2013,33(5):314-317. 被引量：2
-
8袁耿彪.甲状腺癌中的基因突变及其在诊断治疗中应用的研究进展[J].中国肿瘤生物治疗杂志,2009,16(3):305-309. 被引量：6
