期刊文献+

创伤性脑损伤模型的延续与完善:二次脑损伤模型 被引量:6

Developing experimental models to address traumatic brain injury with secondary brain insult
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摘要 随着人类社会工业化、现代化进程的快速发展,创伤性脑损伤(traumaticbraininjury,TBI)~不断上升趋势,其发生的增长率(21%)已超过全球人口的增长率(6%),被学者们称之为“静息性流行病”,现已成为全球关注的社会公共卫生问题。TBI患者除受原发机械性外力直接损伤外,
出处 《中华神经医学杂志》 CAS CSCD 北大核心 2013年第4期426-429,共4页 Chinese Journal of Neuromedicine
基金 宁波市自然科学基金(2011A610041)
关键词 颅脑外伤 二次脑损伤 模型 动物 Traumatic brain injury Secondary brain insult Model, animal
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参考文献36

  • 1Hayward P. Traumatic brain injury: the signature of modem conflicts[J]. Lancet Neurol, 2008, 7(3): 200-201.
  • 2Maas AI, Marmarou A, Murray GD, et al. Prognosis and clinical trial design in traumatic brain injury: the IMPACT study [J]. J Neurotrauma, 2007, 24(2): 232-238.
  • 3费舟,章翔.二次脑损伤[J].中华神经外科疾病研究杂志,2006,5(5):471-473. 被引量:42
  • 4Wang HC, Ma YB, Experimental models of traumatic axonal injury [J]. J Clin Neurosci, 2010, 17(2): 157-162.
  • 5Dennis AM, Haselkorn ML, Vagni VA, et al. Hemorrhagic shock after experimental traumatic brain injury in mice: effect on neuronal death[J]. J Neurotrauma, 2009, 26(6): 889-899.
  • 6Navarro JC, Pillai S, Cherian L, et al. Histopathological and behavioral effects of immediate and delayed hemorrhagic shock after mild traumatic brain injury in rats[J]. J Neurotrauma, 2012, 29(2): 322-334.
  • 7白红民,费舟,章翔,刘恩渝,李志刚,公方和,刘先珍,梁景文.大鼠二次脑损伤模型的建立[J].中华创伤杂志,2002,18(4):214-217. 被引量:11
  • 8Stochetti N, Furlan A, Volta F. Hypoxemia and arterial hypotension at the accident scene in head injury[J]. J Trauma, 1996, 40(5): 764-767.
  • 9Nelson LR, Auen EL, Bourke RS, et al. A comparison of animal head injury models developed for treatment modality evaluation [R]. New York, Raven, 1982:117-128.
  • 10Ishige N, Pitts LH, Berry L, et al. The effect of hypoxia on traumatic head injury in rats: alterations in neurologic function, brain edema, and cerebral blood flow [J]. J Cereb Blood Flow Metab, 1987, 7(6): 759-767.

二级参考文献23

  • 1路红社,朱诚,粟波,张光霁,江基尧.大鼠颅脑伤后血糖变化[J].第二军医大学学报,1996,17(4):333-335. 被引量:11
  • 2Sawauchi S,Beaumont A,Signorettis S,et al.Diffuse brain injury complicated by acute subdural hematoma and secondary insults in the rodents:the effect of surgical evacuation[J].Acta Neurochir Suppl,2002,81:241-242.
  • 3Beaumont A,Marmarou A,Fatouros P,et al.Secondary insults worsen blood brain barrier dysfunction assessed by MRI in cerebral contusion[J].Acta Neurochir Suppl,2002,81:217-219.
  • 4Chen Y,Swanson RA.Astrocytes and brain injury[J].J Cereb Blood Flow Metab,2003,23(2):137-149.
  • 5Tacconi MT.Neuronal death:is there a role for astrocytes[J].Neurochem Res,1998,23(5):759-765.
  • 6Fischer S,Wobben M,Kleinstuck J,et al.Effect of astroglial cells on hypoxia-induced permeability in PBMEC cells[J].Am J Physiol Cell Physiol,2000,279:C935-944.
  • 7Frey,Lauren C.Epidemiology of posttraumatic epilepsy:a critical review[J].Epilepsy,2003,44(Suppl 10):11-17.
  • 8Yokoi I,Toma J,Liu J,et al.Adenosines scavenged hydroxyl radicals and prevented posttraumatic epilepsy[J].Free Radic Biol Med,1995,19(4):473-479.
  • 9Meyerhoff JL,Lee JK,Rittase BW,et al.Lipoic acid pretreatment attenuates ferric chloride-induced seizures in the rat[J].Brain Res,2004,1016(2):139-144.
  • 10Wang X,Ong W,Connor J.Increase in ferric and ferrous iron in the rat hippocampus with time after kainate-induced excitotoxic injury[J].Experimental Brain Research,2002,143(2):137-148.

共引文献101

同被引文献56

  • 1邱炳辉,方陆雄,漆松涛,张永明.急性颅脑损伤并全身炎症反应综合征的预后分析[J].中华急诊医学杂志,2007,16(2):147-150. 被引量:20
  • 2Borovikova LV,Ivanova S,Zhang M,et al.Vagus nerve stimulation attenuates the systemic inflammatory responses to eodotoxin[J].Nature,2000,405(6785):458-462.
  • 3Li L,Lu J,Tay SS,et al.The function of microglia,either neuroprotection or neurotoxicity,is determined by the equilibrium among factors released from activated microglia in vitro[J].Brain Res,2007,1159:8-17.
  • 4Lu J,Goh SJ,Tng PY,et al.Systemic inflammatory response following acute traumatic brain injury[J].Front Biosci,2009,14:3795-3813.
  • 5Yan EB,Hellewell SC,Bellander BM,et al.Post-traumatic hypoxia exacerbates neurological deficit,neuroinfiammation and cerebral metabolism in rats with diffuse traumatic brain injury[J].J Neuroinflammation,2011,8:147.
  • 6Ward JL,Harting MT,Cox CS,et al.Effects of ketamine on endotoxin and traumatic brain injury induced cytokine production in the rat[J].J Trauma,2011,70(6):1471-1479.
  • 7Tamion F,Richard V,Renet S,et al.Protective effects of heme-oxyge-nase expression against endotoxic shock:inhibition of tumor necrosis factor-alpha and augmentation of interleukin-10[J].J Trauma,2006,61(5):1078-1084.
  • 8Wang GH,Jiang ZL,Li YC,et al.Free-radical scavenger edaravone treatment confers neumprotection against traumatic brain injury in rats[J].J Neurotrauma,2011,28(10):2123-2134.
  • 9Vida G,Pena G,Deitch EA,et al.α7-cholinergic receptor mediates vagal induction of splenic norepinephrine[J].J Immunol,2011,186(7):4340-4346.
  • 10韦鹏翔,孙龙,刘四新,刘靖,刘红玲,张小津,李秀芬,周玉嘉,王革生,门斯烨,王卫卫.手厥阴经电刺激对重症脑外伤昏迷患者促醒作用的初步研究[J].北京中医药大学学报,2007,30(10):713-716. 被引量:7

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