百会灸治疗顽固性面瘫及其对免疫球蛋白的影响

Moxibustion at Baihui(GV 20) for intractable facial paralysis and its impacts on immunoglobulin

目的:观察百会灸对顽固性面瘫患者的疗效及对免疫球蛋白IgA、IgG、IgM的影响。方法:将符合纳入标准的120例顽固性面瘫患者随机分为百会灸组和针刺组两组,各60例。百会灸组采用百会灸治疗,针刺组采用针刺治疗,两组均每天治疗1次,以15天为一疗程,治疗前及治疗2个疗程后分别检测两组患者的IgA、IgG、IgM含量,并进行比较。结果:百会灸组总有效率96.7%(58/60),与针刺组疗效相当95.0%(57/60,P>0.05)。两组患者治疗前IgA、IgG、IgM含量比较差异均无统计学意义(均P>0.05),但与正常参考值比较,三者均显著升高(均P<0.05);与治疗前比较,两组治疗后IgA、IgG、IgM含量均显著降低,差异有统计学意义(均P<0.05);两组治疗后比较,百会灸组IgA、IgG、IgM含量显著低于针刺组,两组比较差异有统计学意义(均P<0.05)。结果:顽固性面瘫的发病与免疫球蛋白的异常增高有关,百会灸可显著降低顽固性面瘫患者免疫球蛋白IgA、IgG、IgM含量,这可能是其治疗顽固性面瘫的作用机制之一。

Objective To observe the efficacy of moxibustion at Baihui （GV 20） on intractable facial paralysis and the impacts on immune globulin IgA, IgG and IgM. Methods One hundred and twenty cases of intractable facial paralysis that was in compliance with the inclusive criteria were randomized into a moxibustion group and an acupuncture group, 60 cases in each one. In the moxibustion group, moxihustion was applied at Baihui （GV 20）. In the acupuncture group, the patients were treated with acupuncture, once a day, the treatment of 15 days made one session in two groups. Before treatment and after 2 sessions treatment, the levels of IgA, IgG and IgM were detected respectively for the patients in two groups and compared. Results The difference in the levels of IgA, IgG and IgM was not significant for the patients between two groups （all P〈0.05） before treatment, but the levels of all three indices were increased significantly as compared with the normal reference values （all P〈0.05）. Componed before the treatment, the levels of IgA, IgG and IgM were reduced signifi cantly in two groups after treatment, indicating the significant difference （all P〈 0. 05 ）. In comparison between two groups after the treatment, the levels of IgA, IgG and IgM in the moxibustion group were lower sig nificantly than those in the acupuncture group, presenting the significant difference after treatment （all P〈 0. 05）. Conclusion The ottack of intractable facial paralysis is relevant with the abnormal increase of immunoglobulin. Moxibus tion at Baihui （GV 20） reduces significantly the levels of IgA, IgG and IgM for the patients with intractable facial paraly sis, which is probably one of the mechanisms in the treatment of intractable facial paralysis.