肿瘤干细胞靶向给药系统的研究进展

Progress in the study of targeted drug delivery systems for cancer stem cells

本文通过查阅国内外文献,对肿瘤干细胞的发现、分离鉴定方法与靶向肿瘤干细胞给药系统的研究进展进行了综述。研究认为,肿瘤干细胞是导致肿瘤化疗耐药和肿瘤治疗失败的主要原因,目前肿瘤干细胞靶向给药系统的研究已经取得了较大的进展。肿瘤干细胞的研究及其靶向治疗将为肿瘤的临床治疗带来新希望。

The discovery, sorting and identification methods as well as targeted drug delivery systems for cancer stem cells （CSCs） have been reviewed by consulting the recent research papers. CSCs have been believed to be responsible for the occurrence and development of chemo-resistance, leading to the failure ofchemotherapy. Much progress has been made in the approaches for CSCs targeting drug delivery systems. The understanding and targeted drug delivery systems for CSCs are promising to provide an alternative for cancer therapy.