食管颗粒细胞瘤超声内镜图像的计算机分析研究

Analysis and research of the endoscopic ultrasonography image of esophageal granular cell tumor bycomputer software

目的应用图像分析软件对食管颗粒细胞瘤（GCT）的超声内镜图像进行分析研究，探索其诊断和鉴别诊断价值。方法经病理及免疫组织化学检查确诊的食管GCT和食管平滑肌瘤患者各8例，用图像分析软件测定病灶的超声内镜图像灰度平均值和灰度标准偏差，两组间比较行t检验。结果在内镜图像和超声内镜图像中，食管GCT和食管平滑肌瘤的表现相似。食管GCT和食管平滑肌瘤病灶的超声内镜图像灰度平均值均数分别为67．51和51．76，差异有统计学意义（t=2．225，P=0．043），但二者的超声内镜图像灰度标准偏差均数差异无统计学意义（13．54比13．12，t=0．225，P=0．825）。结论可通过比较食管GCT和食管平滑肌瘤超声内镜图像的灰度平均值来提高超声内镜诊断食管GCT的准确率。

Objective To analyze endoscopic ultrasonography （EUS） image of esophageal granular cell tumor （GCT） by computer image analysis software, and to explore its diagnostic and differential diagnostic value. Methods Eight esophageal GCT and eight leiomyomas confirmed by pathological and immunohistochemical examination were collected, mean gray value and gray value standard deviation of EUS image of the leisons were analyzed by computer image analysis software. The comparison of two groups was analyzed by t test. Results The endoscopic and ultrasound images of esophageal GCT and leiomyomas were similar. The mean gray value of EUS image of esophageal GCT and esophageal leiomyomas was 67.51 and 51.76, the difference was statistically significant （t= 2. 225,P= 0. 043）. However, there was no significant difference in the standard deviation of gray value （13.54 vs 13.12, t=0. 225, P=0. 825）. Conclusion The accuracy of GCT diagnosed by EUS could be increased by comparing the gray values of EUS images of esophageal GCT and leiomyomas.