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高压氧下呼气末正压通气对犬颅内压的影响 被引量：1

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摘要 机械通气患者行高压氧（hyperbaricoxygen，HBO）治疗引起国外学者的关注^[1]，许多危重症患者需要应用呼气末正压（positiveend—expiratory pressure，PEEP）才能维持氧合。研究证明，常压下应用PEEP在发挥有效生理作用的同时，会导致患者颅内压（intracranialpressure，ICP）升高和脑灌注压（cerebralperfusionpressure，CPP）下降^[2-3]。
作者 秦金燕 高光凯 孙擎 吴镝 吕福祥 杨鹰 于涛
机构地区 解放军第四〇一医院全军临床航海医学中心山
出处 《中华航海医学与高气压医学杂志》 CAS CSCD 北大核心 2013年第1期60-62,共3页 Chinese Journal of Nautical Medicine and Hyperbaric Medicine
基金 全军临床高新技术重点课题项目（2010GXJS023）
关键词 呼气末正压通气 颅内压 高压氧 机械通气患者 危重症患者 国外学者 生理作用 PEEP
分类号 R45 [医药卫生—治疗学]
  • 相关文献

参考文献15

  • 1Haddon R. Anaesthesia and intensive care in the hyperbaric chamber. Curr Anaesth & Crit Care,2002,13 (5) :263-269.
  • 2Georgiadis D, Schwarz 5, Baumgartner RW, et al. Influence of positive end- expiratory pressure on intracranial pressure and cerebral perfnsion pressure in patients with acute stroke. Stroke, 2001,32(9) :2088-2092.
  • 3Huseby JS, Pavlin EG, Butler J. Effect of positive end - expiratory pressure on intracranial pressure in dogs. J Appl Physiol, 1978,44 ( 1 ) :25- 27.
  • 4Rockswold SB, Rockswold GL, Zaun DA, et al. A prospective, randomized clinical trial to compare the effect of hyperbaric to normoharic hyperoxia on cerebral metabolism, intracranial pressure, and oxygen toxicity in severe traumatic brain injury. J Neurosurg,2010,112(5 ) : 1080-1094.
  • 5孙建森,黎海涛,应大君.监测烧伤实验犬颅内压椎管内置管技术的探讨[J].中国比较医学杂志,2007,17(3):174-176. 被引量：4
  • 6Heuer JF, Sauter P, Barwing J, et al. Effects of high - frequency oscillatory ventilation on systemic and cerebral hemodynamics and tissue oxygenation: an experimental study in pigs. Neurocrit Care, 2012,17 ( 2 ) :281 - 292.
  • 7Weaver LK. Hyperbaric oxygen in the critically ill. Crit Care Med,2011,39 (7) : 1784-1791.
  • 8闫润民,卢亦成,于明琨,楼美清,张光霁,朱诚.呼气末正压通气对犬脑内血肿高颅压的影响[J].第三军医大学学报,2007,29(6):513-515. 被引量：8
  • 9Stevens RD, Lazaridis C, Chalela JA. The role of mechanical ventilation in acute brain injury. Neurol Clin,2008,26 ( 2 ) : 543- 563.
  • 10Hayakawa T, Kanai N, Kumda R, et al. Response of cerebrospinal fluid pressure to hyperbaric oxygenation. J Neurol Neurosurg Psychiatry, 1971,34 ( 5 ) : 580- 586.

二级参考文献10

  • 1Videtta W, Villarejo F, Cohen M, et al. Effects of positive end-expiratory pressure on intracranial pressure and cerebral perfusion pressure[J]. Acta Neurochir Suppl, 2002, 81 : 93-97.
  • 2Huynh T, Messer M, Sing R F, et al. Positive end-expiratory pressure alters intracranial and cerebral perfusion pressure in severe traumatic brain injury[J]. J Trauma, 2002, 53(3) : 488 -492.
  • 3Lowe G J, Ferguson N D. Lung-protective ventilation in neurosurgical patients[J]. Curr Opin Crit Care, 2006, 12( 1 ) : 3 -7.
  • 4Huseby J S, Pavlin E G, Butler J. Effect of positive end-expiratory pressure on intracranial pressure in dogs [ J ]. J Appl Physiol, 1978,44(1): 25-27.
  • 5Aidinis S J, Lafferty J, Shapiro H M. Intracranial responses to PEEP[J]. Anaesthesiology, 1976, 45(3) : 275 -286.
  • 6Georgiadis D, Schwarz S, Banmgartner R W, et al. Influence of positive end-expiratory pressure on intracranial pressure and cerebral perfusion pressure in patients with acute stroke[J]. Stroke, 2001,32(9) :2088 - 2092.
  • 7Muench E, Bauhuf C, Roth H, et al. Effects of positive end-expiratory pressure on regional cerebral blood flow, intracranial pressure, and brain tissue oxygenation[J]. Crit Care Med, 2005, 33(10) : 2367 -2372.
  • 8Caricato A, Conti G, Della-Corte F, et al. Effects of PEEP on the intracranial system of patients with head injury and subarachnoid hemorrhage: the role of respiratory system compliance[J]. J Trauma, 2005,58(3) : 571 -576.
  • 9Mousavi,Kolonnja A,Schaden E,et al.Intracranial pressurealterations during controlled intramedullary reaming of femoral fractures:an animal study[J].Injury,2001 32(9):679-682.
  • 10Rieger A,Rainov NG,Sanchin L,et al.Is it useful to measure supratentorial ICP in the presence of a posterior fossa lesion? Absence of transtentorial pressure gradients in an animal model[J].Br J Neurosurg,1999,13(5):454-458.

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中华航海医学与高气压医学杂志
2013年 第1期

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