液相色谱/串联质谱法测定生活饮用水中的双酚A方法验证

Method validation on determination of BPA in drinking water by liquid chromatography-triple quadrupole mass spectrometer

目的:验证液相色谱/串联质谱法(LC/MS/MS)测定生活饮用水中的双酚A。方法:水样经玻璃纤维滤膜过滤,上LC/MS/MS用多反应监测模式检测,外标法定量。结果:浓度2μg/L～200μg/L范围内线性关系良好,相关系数r>0.999,检出限1μg/L。对江苏地区45个水样进行检测,全部未检出双酚A。结论:本方法简便、快速、准确,可以满足生活饮用水中的双酚A测定要求。

Objective： To validate the determination of BPA in drinking water by Liquid Chromatography - Triple Quadrupole Mass Spectrometer. Methods： The sample was tilted through glass tiber tilter and detected by Liquid Chromatography- Triple quadrupole mass spectrometer. Results： The correlation coefficients of linear calibration curves were over 0. 999 within the BPA concentration range of 2 μg/L - 200 μg/L. The detection limits was 1 μg/L. Conclusion： The method can be used routinely for the determination of BPA in drinking water.