摘要
An efficient and eco-friendly method is reported for the synthesis of 2-substituted-2,3-dihydroquinazolin-4(1H)-ones from direct cyclocondensation of anthranilamide with aldehydes and ketones using N-propylsulfamic acid supported onto magnetic Fe304 nanoparticles (MNPs-PSA) as a recoverable and recyclable nanocatalyst in good to excellent yields in water at 70 ℃, The catalyst was readily separated using an external magnet and reusable without significant loss of their catalytic efficiency,
An efficient and eco-friendly method is reported for the synthesis of 2-substituted-2,3-dihydroquinazolin-4(1H)-ones from direct cyclocondensation of anthranilamide with aldehydes and ketones using N-propylsulfamic acid supported onto magnetic Fe304 nanoparticles (MNPs-PSA) as a recoverable and recyclable nanocatalyst in good to excellent yields in water at 70 ℃, The catalyst was readily separated using an external magnet and reusable without significant loss of their catalytic efficiency,