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microRNA在结直肠肿瘤中的研究进展 被引量：3

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摘要 结直肠癌是最常见的恶性肿瘤之一,全世界结直肠癌患者每年新增123万例,其中有60万患者死亡[1].通过各种筛查手段早期发现、早期治疗可显著降低其病死率.微小RNA（microRNA,miRNA）是一种非编码RNA,目前已成为肿瘤研究的热点之一.研究[2-5]表明,miRNA表达失调与多种恶性肿瘤密切相关,且具有一定的特异性,有望成为肿瘤筛查、诊断及预后评估的生物学标记物之一.现就miRNA在结直肠肿瘤中的研究进展进行综述.
作者 吴晨鹏 张志勇
机构地区 河北省唐山市工人医院病理科
出处 《河北医科大学学报》 CAS 2013年第3期370-372,共3页 Journal of Hebei Medical University
关键词 结直肠肿瘤 微RNAS 综述文献
分类号 R735.35 [医药卫生—肿瘤]
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  • 1Duffy MJ. Clinical uses of tumor markers: a critical review. Crit Rev Clin Lab Sci 2001; 38:225-262.
  • 2Thomas CM, Sweep CG. Serum tumor markers: past, state of the art, and future, lnt J Biol Markers 2001; 16:73-86.
  • 3Duffy MJ. Role of tumor markers in patients with solid cancers: a critical review. Eur J lntern Med 2007; 18:175-184.
  • 4Roulston JE. Limitations of tumour markers in screening. Br J Surg 1990; 77:961-962.
  • 5Esquela-Kerscher A, Slack FJ. Oncomirs - microRNAs with a role in cancer. Nat Rev Cancer 2006; 6:259-269.
  • 6Calin GA, Croce CM. MicroRNA signatures in human cancers. Nat Rev Cancer 2006; 6:857-866.
  • 7Chen C, Ridzon DA, Broomer A J, et al. Real-time quantification of microRNAs by stem-loop RT-PCR. Nucleic Acids Res 2005; 33:e179.
  • 8Tang F, Hajkova P, Barton SC, Lao K, Surani MA. MicroRNA expression profiling of single whole embryonic stem cells. Nucleic Acids Res 2006; 34:e9.
  • 9Hafner M, Landgraf P, Ludwig J, et al. Identification of microRNAs and other small regulatory RNAs using cDNA library sequencing. Methods 2008; 44:3-12.
  • 10Volinia S, Calin GA, Liu CG, et al. A microRNA expression signature of human solid tumors defines cancer gene targets. Proc Natl Acad Sci USA 2006; 103:2257-2261.

共引文献982

同被引文献26

  • 1戴丹,徐燕丽.MicroRNA与恶性淋巴瘤相关性研究进展[J].河北医科大学学报,2009,30(10):1106-1108. 被引量：2
  • 2徐皓,张玉华,吴文溪.微RNA与肿瘤[J].国际肿瘤学杂志,2006,33(10):731-733. 被引量：1
  • 3LIU A, XU X. MicroRNA isolation from formalin-fixed, paraffin- embedded tissues[ J]. Methods Mol Biol,2011,724:259 - 267.
  • 4FRANCI C, ZHOU J, JIANG Z, et al. Biomarkes of residual disease, disseminated tumor cells, and metastases in the MMT- PyMT breast cancer model[J]. PLoS One ,2013,8(3 ) :e58183.
  • 5APPAIAH HN, GOSWAMI CP, MINA LA, et al. Persistent upregulation of U6 : SNORIM4 small RNA ratio in the serum of breast cancer patients [ J ]. Breast Cancer Res, 2011 , 13 ( 5 ) : R86.
  • 6PRUDNIKOVA TY, MOSTOVICH LA, KASHUBA VI, et al. miRNA-218 contributes to the regulation of D-glucuronyl C5- epimerase expression in normal and tumor breast tissues [J]. Epigenetics ,2012,7 (10) : 1109 - 1114.
  • 7WARD A, BALWIERZ A, ZHANG JD, et al. Re-expression of microRNA-375 reverses both tamoxifen resistance and accompanying EMT-like properties in breast cancer [ J ]. Oncogene,2013,32(9) :1173 - 1182.
  • 8GODFREY TE, KIM SH, CHAVIRA M, et al. Quantitative mRNA expression analysis from formalin-fixed, paraffin-embeddod tissues using 5 "nuclease quantitative reverse transcription-polymerase chain reaction [ J ]. J Mol Diagn ,2000,2 ( 2 ) : 84 - 91.
  • 9VON AHLFEN S, MISSEL A, BENDRAT K, et al. Determinants of RNA quality from FFPE samples [ J ]. PLoS One, 2007,2 ( 12 ) : e1261.
  • 10MASUDA N, OHNISHI T, KAWAMOTO S, et al. Analysis of chemical modification of RNA from formalin-fixed samples and optimization of molecular biology applications for such samples [ J ]. Nucleic Acids Res, 1999,27 (22) :4436 - 4443.

引证文献3

二级引证文献3

河北医科大学学报
2013年 第3期

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