摘要
目的:研究隔附子饼灸对佐剂性关节炎大鼠"足三里"穴位局部Eraf基因表达的影响。方法:SD大鼠随机分为空白组、模型组、隔附子饼灸组。造模后第7 d,隔附子饼灸组灸"足三里"穴5壮,灸后2 h,立即取"足三里"穴位局部组织(0.5 cm×0.5 cm),用实时荧光定量聚合酶链式反应检测Eraf的表达。结果:Eraf表达水平:模型组与空白组相比,显著下调(P<0.05);隔附子饼灸组与模型组相比,显著上调(P<0.05)。结论:隔附子饼灸"足三里"能显著上调穴位局部Eraf基因的表达。
Objective：To study the effects of moxibustion at Zusanli（ST36） acupoint on the expression of Eraf gene in adjuvant arthritis（AA） rats.Methods：SD rats were randomly divided into control group,model group,aconite moxibustion group.7 days after AA model established,aconite moxibustion were performed for five Zhuang.2 hours after treatment,the moxibustioned Zusanli（ST36） tissue（0.5 cm×0.5 cm） were took immediately in which the expression Eraf was detected by real-time quantitative PCR.Results：The expression of Eraf was significantly down-expressed in model group（vs.control group,P0.05）.Aconite moxibustion could increase the expression of Cox7a2（vs.model group,both P0.05）.Conclusion：Eraf gene could be significantly up-expressed by moxibustion at ＂Zusanli（ST36）＂ acupoint.
出处
《成都中医药大学学报》
2013年第1期15-18,共4页
Journal of Chengdu University of Traditional Chinese Medicine
基金
国家重点基础研究发展("973")计划(编号:2009CB522903)
