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Patched-1和Gli-1在尖锐湿疣皮损中的表达及意义 被引量：2

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摘要 目的探讨Hedgehog(Hh)信号通路在尖锐湿疣皮损中的表达及意义。方法通过免疫组化方法检测尖锐湿疣皮损和正常皮肤中Hh信号通路分子Patched-1和Gli-1表达的情况。结果尖锐湿疣患者皮损中Patched-1和Gli-1阳性表达均明显高于正常对照组,差异均有统计学意义(P<0.05)。结论 Patched-1和Gli-1在尖锐湿疣患者皮损表达升高,提示Hh信号通路可能参与尖锐湿疣的发病过程。
作者 李萍 冯世军 朱文胜 艾东方 杨秀芳
机构地区 沧州市中心医院 青县人民医院
出处 《山东医药》 CAS 2012年第36期88-89,F0003,共3页 Shandong Medical Journal
关键词 尖锐湿疣 Patched-1 Gli-1 HEDGEHOG信号通路 免疫组化
分类号 R752.53 [医药卫生—皮肤病学与性病学]
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参考文献12

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二级参考文献27

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山东医药
2012年 第36期

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