慢性肝病患者脾硬度值与肝硬度值的相关分析

Spleen stiffness measurement and liver stiffness measurement in patients with chronic liver diseases

目的研究慢性肝病患者脾脏硬度(SSM)值与肝脏硬度(LSM)值的相关性。方法选择200例慢性肝病患者,其中肝硬化组120例,肝炎组80例。采用瞬时弹性成像技术检测两组SSM及LSM程度,并对其SSM值和LSM值进行相关分析。结果肝硬化组、肝炎组的SSM值与LSM值均有显著相关性(r分别为0.377、0.314,P分别为0.000、0.005)。结论慢性肝病患者的SSM值与LSM值显著相关,临床联合检测SSM及LSM,可全面地评价慢性肝病患者的病情。

Objective To investigate the correlation of spleen stiffness measurement （SSM） and liver stiffness meas- urement （LSM） in patients with chronic liver diseases. Methods 200 patients with chronic liver diseases were chosen, containing 120 patients with cirrhosis and 80 patients with hepatitis. Spleen stiffness measurement and liver stiffness meas- urement were determined by Fibroscan, then the correlation between SSM and LSM was analysed. Results In the patients with cirrhosis or hepatitis, there were both significant correlations between SSM and LSM （ r = 0. 377, P = 0. 000 ; r=0.314, P =0. 005 ）. Conclusion In patients with chronic liver diseases, there is a significant correlation between SSM and LSM, and their combinative detection could assess of disease condition of the patients with chronic liver diseases more comprehensively and synthetically.