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心房颤动发生与糖化血红蛋白水平的关系 被引量:5

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摘要 目的探讨心房颤动(房颤)发生与糖化血红蛋白(HbA1c)水平的关系。方法选择心血管疾病患者260例,其中经心电图检查新确诊为房颤83例(房颤组)、无房颤177例(无房颤组);检测两组HbA1c、血脂及心电图。HbA1c<6.3%为低HbA1c,≥6.3%为高HbA1c。结果 260例患者的房颤发生率为31.9%(83/260)。与非房颤组比较,房颤组年龄大,有糖尿病史者比例高,HbA1c及TC明显升高(P<0.01或<0.05);高HbA1c患者的房颤发生率为41.0%(64/156),明显高于低HbA1c者[18.3%(19/104)],差异有统计学意义(P<0.01)。校正了年龄、性别、高血压、冠心病、糖尿病、TC、TG等因素后,HbA1c升高为房颤发生的独立危险因素,其危险度为1.720,95%可信区间为1.364~2.169(P<0.01)。结论 HbA1c升高是房颤发生的独立危险因素,尤其是HbA1c≥6.3%者的房颤发生率明显升高。
出处 《山东医药》 CAS 2012年第45期41-42,共2页 Shandong Medical Journal
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