四种新型因子与冠心病关系的研究进展

The Progress on the Research of the Four New Factors and Coronary Heart Disease

自冠心病被发现以来,其危险因子就不断地被发现,现已发现了约200多种冠心病的危险因子,既往已知的体内的危险因子有血脂异常、纤维蛋白原、血清同型半胱氨酸、妊娠相关性血浆蛋白A、白介素-6等。近些年来随着研究人员对冠心病的不断深入研究,又发现了一些新的体内的危险因子,如:血浆超敏C反应蛋白、D-二聚体、血管性血友病因子和脂蛋白相关磷脂酶A2等,临床上通过对这些新的危险因子的检测分析,有助于对冠心病发生发展、诊断、治疗及预后的判断。

The risk factors of coronary heart disease are being discovered constantly since the disease was known by people. It is about 200 kinds of risk factors that has been discovered up to now. Previously known risk factors in the body including ： dyslipidemia, fibrinogen, serum with semi-hazy acid, pregnancy-associated plasma protein A, interleukin-6 etc. Scientists reveal some new risk factors of coronary heart disease in recent years, for example： hypersensitive C-reactive protein, D-dimer, von Willebrand factor, lipoprotein-associated phospholipase A2 and so on, the analysis of the new risk factors of coronary heart disease will contribute to the judgment of diagnose, therapy, development and progress of coronary heart disease.