摘要
目的研究冠心病患者的CD41水平,以及经皮冠脉介入治疗(PCI)术对CD41水平的影响。方法测定行PCI术者(235例)及仅行冠状动脉造影(CAG)的患者(121例)手术前及手术后2h的CD41水平。结果术前冠心病患者的CD41水平明显高于非冠心病者(P<0.05)。而在仅行CAG的患者术前与术后CD41水平无明显变化(P>0.05),CD41水平在PCI术后2h高于术前(P<0.05)。结论冠心病患者的血小板活性高于非冠心病者,PCI术可促进血小板激活。
Objective To study CD41 level in patients with coronary artery disease((~AD) and the lnlluence o1 per- cutaneous coronary intervention(PCI). Methods The present study enrolled 235 patients undergoing PCI (PCI group) and 121 patients only undergoing coronary angiography (CAG group). The level of CD41 was detected by flow cytometry. Results The level of CD41 in patients with CAD was significantly higher than that in cases without CAD ( P 〈 0. 05 ). The level of CD41 2 hours after the operation in PCI group was higher than that before PCI ( P 〈 0.05 ). Conclusions The activity of platelet is increased in patients with CAD. Platelet might be activated by PCI.
出处
《实用老年医学》
CAS
2012年第4期312-313,共2页
Practical Geriatrics
基金
广东省卫生厅科技项目(B2003123)
关键词
冠心病
经皮冠状动脉介入治疗
CD41
coronary artery disease
percutaneous coronary intervention
CD41