摘要
目的探讨老年2型糖尿病患者25-羟基维生素D(25-OH-VitD)、血脂水平的变化。方法对在我院住院的41例老年2型糖尿病患者和在门诊健康体检的48例正常老年人进行问卷调查、体格检查和生化指标等检测。结果老年2型糖尿病组的三酰甘油、低密度脂蛋白胆固醇水平明显高于对照组,25-OH-VitD、高密度脂蛋白胆固醇低于对照组;2型糖尿病组中25-OH-VitD低于正常值检出率、血脂异常检出率均高于对照组;25-OH-VitD低于正常值组2型糖尿病发生率高于正常值组。糖尿病发生率与25-OH-VitD、血脂异常均有相关性。结论老年2型糖尿病患者除严格控制血糖外,有必要检测25-OH-VitD、血脂水平,进行及早干预,以早期预防或延缓糖尿病并发症的出现,从而更好地改善生活质量。
Objective To study the relationship between 25-hydroxyvitamin D, blood lipid levels and the incidence of type 2 diabetes mellitus（T2DM） in the elderly. Methods Forty-one elderly patients with T2DM in our hospital and 48 healthy elderly cases received the measurement of questionnaire, physical examination and biochemical parameters. Results The levels of TG, LDL-C in the elderly patients with T2DM were significantly higher, and the levels of 25-hydroxyvitamin D and HDL-C were lower than those in the normal control group ; the detection rates of 25-hydroxyvitamin D lower than noimal and abnormal blood lipid in diabetes group were higher than those in the normal control group. The incidence of T2DM in the patients with a level of 25-hydroxyvitamin D lower than normal was higher than that in the cases with nomal level of 25- hydroxyvitamin D. There were significant correlation between 25-hydroxyvitamin D, abnormal blood lipid and the incidence of diabetes, respectively. Conclusions It is necessary to detect 25-hydroxyvitamin D, blood lipid levels in the elderly pa- tients with T2DM. Very early intervention might prevent or delay the development of diabetic complications.
出处
《实用老年医学》
CAS
2012年第4期323-325,共3页
Practical Geriatrics
