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热休克蛋白10在子宫内膜癌中的表达及意义 被引量:4

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摘要 目的探讨热休克蛋白10(HSP10)在子宫内膜癌中的表达及意义。方法采用免疫组化Envision法检测30例正常子宫内膜、30例增生过长子宫内膜、15例非典型增生子宫内膜、50例子宫内膜癌中HSP10的分布及表达。结果 HSP10在正常子宫内膜、增生过长子宫内膜、非典型增生子宫内膜和子宫内膜癌阳性表达率分别为16.67%(5/30)、43.33%(13/30)、66.67%(10/15)、100.00%(50/50),差异有统计学意义(P<0.001);HSP10的阳性表达程度与子宫内膜癌的肌层浸润深度、宫颈受累情况有关(P<0.05),与手术病理分期、病理分级、组织学类型、腹腔积液细胞学、淋巴结转移无关(P>0.05)。结论 HSP10在子宫内膜癌的发生、发展中可能起着重要作用。
出处 《广东医学》 CAS CSCD 北大核心 2013年第6期928-930,共3页 Guangdong Medical Journal
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