胱抑素C对急性脑梗死患者早期肾损害的检测价值

The Detection Value of Cystatin C on Acute Cerebral Infarction in Early Renal Damage

目的分析胱抑素C对老年急性脑梗死患者合并早期肾功能损害的检测价值。方法取2010年4月-2012年4月间内蒙古自治区人民医院神经内科收治的老年急性脑梗死患者150例作为研究对象,根据有无肾功能损害分为有早期肾功能损害的观察组患者65例,无肾功能损害的对照组患者85例,比较两组患者的肾功能指标及血胱抑素C浓度差异。结果观察组Ccr、CysC明显高于对照组(P<0.01),Scr、Urea和对照组比较差异无统计学意义(P>0.05);且肾功能分级越差,Ccr水平越低、Urea、CysC和Hcy水平越高;在肾功能Ⅰ期和Ⅱ期的患者中,CysC的异常检出率明显高于Scr和Urea的异常检出率。结论胱抑素C是早期发现老年脑梗死患者并发肾功能损害的有效指标之一。

Objective To explore the detection value of cystatin C on acute cerebral infarction in early renal damage. Methods 150 cases of acute cerebral infarction patients were divided into early Impairment of renal function（ n = 65 ） and no Impairment of renal function （ n = 85 ）, renal function and serum cystatin C were recorded and analyzed. Results Ccr and Cys C in observation group were significantly higher than those in control group （P 〈 0.01 ） , there was no significant difference （P 〉 0.05 ） in Set and Urea between the two groups ; the renal function worse, the lower the level of Ccr, Urea, Cys C and Hcy level higher; to patients in phase I and II renal function, the abnormal rate of Cys C was higher than that of Scr and Urea abnormal detection rate. Conclusion Cvstatin C was an effective index of the early renal damage in acute cerebral infarction.